![]() $425 for the standard screen for the three common trisomies the options of screening for fetal sex and for sex chromosome abnormalities are available at no additional charge. >Link to Sonic Healthcare collection centresĮnsure you filter "NIPT/Non-invasive prenatal test". Please contact us for other ordering options. There is a specific request form for this test which must be used (above) to ensure that we have the required information about the woman and her pregnancy to provide an accurate result. There may be limits on the days of the week when samples can be collected (to allow for prompt shipping to the laboratory). Special instructions:Ĭollections must be booked through special collection centres, either at the point of payment on the NIPT portal or by calling 1800 010 447. We recommend that the patient or another adult check the labelling of request form and sample tube. Samples collected into the common specimen tubes cannot be tested. Sample required:īlood collected into one specialised NIPT tube. Download the NIPT request form or order via your Practice Management Software where enabled. We cannot accept a request for NIPT on a standard request form. Request form:Ī special request form is required. Before starting to offer this test to patients, doctors are strongly advised to contact the laboratory on 1800 010 447 for advice and review the information for doctors on our website. This test can be requested by any medical practitioner. The abnormal abundance of a specific chromosome or segment indicates that the fetus may have an abnormality involving that chromosome or segment. Methodology:Īnalysis of millions of fragments of DNA in the maternal plasma provides a measure of the relative abundance of DNA from each chromosome and chromosome segment. Please contact us on 1800 010 447 or at Genetics offers free genetic counselling for eligible patients who receive a result indicating a high probability of a chromosome abnormality. We can also provide you with a list of genetic counselling services should this be required. Sonic Genetics can provide literature to assist these doctor-patient discussions. The request form requires both the requesting doctor and the patient to affirm that such consent has been provided. ![]() This is particularly important with genome-wide NIPT as the performance, interpretation and management of this test are different to standard NIPT for the common trisomies for further information, please refer to the NIPT Options technical bulletin. The requesting practitioner is responsible for obtaining and documenting this consent. Ethical considerations:Īll antenatal tests for fetal conditions raise important issues regarding informed consent from the patient. You will find further information for doctors and patients about the test in our dedicated section on NIPT. to the complex biology of pregnancy, rather than reflecting technical flaws in the design or delivery of NIPT. They can be due to placental mosaicism i.e. There is always a chance of an NIPT result being a false positive.įalse negative and false positive results may occur with any form of NIPT. There is always a small chance of an NIPT result being a false negative.Ī result indicating high probability of a specific disorder should be confirmed by invasive cytogenetic testing, for example, CVS or amniocentesis with cytogenetic analysis, before making major decisions regarding the pregnancy. Utility:Ī result indicating low probability of a specific disorder is usually reassuring regarding that disorder, but it must be interpreted in the light of other factors which influence the risk of the fetus having abnormal chromosomes. There is also the option for a genome-wide NIPT screen which covers chromosome macro-duplications and -deletions (larger than seven million base pairs) and rare monosomies and trisomies. There is the option to screen for fetal sex (no charge) or sex chromosome abnormalities such as monosomy X (Turner syndrome), XXY (Klinefelter syndrome), XYY and XXX (no charge) or both. ![]() The standard disorders covered by NIPT are: ![]() Non-invasive prenatal testing is a test of a pregnant woman's blood to screen for various chromosomal disorders in the developing fetus. ![]()
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